Clark County commissioners gave billionaire Tilman Fertitta the green light to develop a towering hotel-casino on the Strip.

The commission on Wednesday approved Fertitta’s plans for a 43-story, 2,420-room project in the tourist-choked casino corridor. The upscale resort, at the southeast corner of Las Vegas Boulevard and Harmon Avenue, would include restaurants, convention space, a spa, a wedding chapel, an auto showroom and a roughly 2,500-seat theater.

It would also feature suites and villas, VIP salons, and a bar and lounge for high-limit gamblers, building plans indicate.

Fertitta has owned downtown Las Vegas’ Golden Nugget for years. But the proposed high-rise on the Strip would give him a foothold in the heart of America’s casino capital, and his plans follow a surge of other real estate activity on Las Vegas Boulevard over the past year or so.